MS Wil GmbH

P.O. Box 1426  - CH 8048 Zurich
Phone +41 71 912 12 77
Fax +41 71 912 12 79
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This source design is from University of Washington and your choice if you are seeking a Nano LC source with

  • ultimate flexibility
  • have to deal with budget constrains
  • need to upgrade as research develops further

Thanks to https://proteomicsresource.washington.edu/ esp. Priska von Haller and Michael J. MacCoss for putting flexible design together

This UWPR nanospray source comes as a kit can be adjusted to fit all Thermo instruments such as LTQ, Orbitrap, Q-Exactive, TSQ Quantiva, Thermo Orbitrap Fusion just to name a few.

Key features:

  • lower flow rates over standard ESI sources, does not need drying gas or thermal heating,
  • Increase the sensitivity compared to higher flow ESI
  • Higher tolerance to a wide variety of liquid compositions than conventional ESI

This kit source offers you great flexibility: It will not only accommodate in house packed columns of all length but also commercial columns, as well as configurations with traps, spray tips etc.

You can order your build kit with high quality Video systems just as the once used by Proxeon.

Proxeon Video system Proxeon Video system 2

The source can be customized to your specific needs: e.g. mounting of cameras, LED lights, Laserpointer light, ABirds, column ovens (PST pencil heaters work great) or anything else you can think of……

Additionally this UWPR nanospray source can be used in conjunction with the Thermo probes

(static , dynamic and packed tip probe)

The open design allows for leaks to be detected immediately. This platform can also be used with the adapter ring of the Thermo source, eliminating the need to machine the adapter bracket.

This UWPR nanospray source is proven on various Thermo instruments, mainly on Orbitrap.

If you`re interested - please contact This email address is being protected from spambots. You need JavaScript enabled to view it.

DiY NanoESI source on Thermo Orbitrap including Butterfly and ABirdDiY NanoESI source on Thermo Orbitrap including Butterfly and ABird

UWPR NSI source on the Fusion with trap and 30cm analytical column

UWPR NSI source on the QExactive Plus with trap and 30cm analytical column and optional LED light

 

Paperspray and Cold Plasma ionisation are optional modes of ionisation available with the UWPR source kit.

Paperspray Option on UWPR source 

Paperspray Option top view

Paperspray closeup

 

Plasma Ionisation:

Cold Plasma Ionisation on the UWPR Ion Source