MagReSyn Protein G (2 ml)
MagReSyn® Protein G is a proprietary magnetic polymeric microparticle support that provides a simple and convenient method for highly specific capture of various immunoglobulins from biological samples. Recombinant Streptococcal Protein G (lacking the albumin binding region for increased immunoglobulin specificity) is covalently linked to the magnetic microparticles reducing leaching during your experimentation, and potentially stabilizing the Protein G for applications in non-standard conditions. Protein G binds to most mammalian immunoglobulins with greater affinity than Protein A, including human IgG3 and rat IgG2a. It does not react with human IgM, IgD or IgA.

MagReSyn Technology Description

New miniaturized, high throughput technologies for bioseparation, diagnostics, DNA sequencing, flow cytometry, drug discovery, proteomics and genomics are in many instances reliant on attachment of functional biological molecules to a microsphere support. The vast array of life sciences applications include: capture reagents for immunoassay (fluorescence, enzyme linked etc); surfaces for immunoprecipitation; diagnostic assays; fluorescence microscopy; flow/imaging cytometry; magnetic cell separation; molecular diagnostics; agglutination tests; nucleic acid separation and protein separation among others.

Conventional microparticle technologies use solid or porous/cracked microparticles with binding of biological molecules limited to the surface, a key factor constraining performance and the development of new applications for microparticle technologies and products. We have developed a novel (patented) microparticle technology platform, comprising a hyper-porous polymer matrix that allows penetration of biological and synthetic molecules throughout the volume of the microparticles. This offers exceptionally high surface area for binding of molecules and allows performance that is orders of magnitude greater than alternate technologies. The binding capacity serves as a major performance contributor to the number of applications and versatility for end-user applications by and further enables miniaturization, increased sensitivity and reducing the cost of R&D.