What you need to know about the ABIRD (Active Background Ion Reduction Device)

What you need to know about the ABIRD (Active Background Ion Reduction Device)

ABIRD (or Active Background Ion Reduction Device) is a popular accessory for nanospray-powered mass spectrometers, and has been approved for use on all Thermo Scientific instruments and nanospray sources. ABIRD will consistently: Isolate the instrument from changing background ions, which is critical for extended quantitative or comparative analyses.Reduce background ion signals, enhancing S/N ratio quite dramatically in many cases. These are benefits that only an ABIRD can provide, making it a smart enhancement for any nanospray ESI/LC-MS system. Many users hope to demonstrate improved peptide detection with ABIRD installed, but get frustrated when they cannot easily do so. Given the…
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Make near perfect glass capillary ends, using the Capillary Polishing Station

Make near perfect glass capillary ends, using the Capillary Polishing Station

Looking for a way to make near perfect glass capillary ends in the lab, to give optimal chromatographic response and robustness? The new and improved Capillary Polishing Station 2 (CPS-2) from ESI Source Solutions allows you to do so. This device provides a simple means to make clean polished ends on various OD glass capillaries tubing and 1/16” PEEK tubing as well. This is essential for reliable high-sensitivity capillary chromatography. The device consists of two parts, the polishing base and the capillary jig, shown below. The new Capillary Polishing Station has three disks of lapping film, a 30 micron (um)…
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Making Meaningful nLC Connections

Making Meaningful nLC Connections

Often our customers ask us: “How do I make my connections work in my nanoLC-MS set-up?” or a variant of this phrase. In this article we will provide you with our insight into this misty territory, with many options and pitfalls. The first question for you to answer is: “What do I want to connect and with what purpose”. Is it “just” a coupling between a transfer line and a column or emitter, or do you want to turn the connection into a Liquid Junction at the same time. In latter case, you may wish to look into some electrical…
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