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Background Noise Reduction

Active Background Ion Reduction Device (ABIRD)


ABIRD – the Active Background Ion Reduction Device for nanospray has been used in top labs worldwide to improve signal-to-noise ratios of peptides and produces a consistent low-level background ion signal. ABIRD is most effective at improving peptide identification on older ion trap instruments that have a lower duty cycle than the newest models.

ABIRD

ABIRD affords you a consistent background ion signal that allows the ion trap to fill with interesting peptide ions rather than pesky background ions. It can help keep those internal lenses and quads cleaner, as the inlet is isolated from dust and debris that might enter the instrument. The ABIRD has mounting solutions to the Flex Ion and Easy Spray sources, and is approved for use on Thermo instruments.




What will ABIRD do for your nano-ESI-MS system?

  • Firstly, ABIRD can reduce background ion signal in full MS during nanospray-ESI analyses.
  • Secondly, ABIRD can isolate your instrument from spikes in lab air, vital for extended quantitative analyses.
  • ABIRD can also enhance signal-to-noise ratios across a wide mass range.
  • Besides that, ABIRD can impart a consistent low-level chromatographic baseline across a full gradient.
  • And as last, ABIRD can improve the identification of proteins in complex low-level protein mixtures*.



ABird installed on a Thermo Scientific Orbitrap Exploris™ 480
Data courtesy of Dr. Wolfgang Bildl, University of Freiburg




ABIRD uses no supplied gasses, just eco-friendly high capacity chemical filters. ABIRD has been fitted to a variety of sources and instrument combinations including Thermo Fisher, Waters, Bruker, Proxeon, New Objective, and Advion.

* Top labs have repeatedly shown ABIRD improving peptide identification up to 50% on complex low-level samples. This can be done when you have excellent capillary chromatography and nanospray interface, a well tuned and calibrated instrument and adequate search engines for analyzing the data.



In order to find out more information on how to use ABIRD succesfully, please download this Tech Note:

ABIRD Tech Note

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