Sonation Column Ovens – developed with the objective of improving nanoESI.
Developed at the Max-Planck-Institute of Biochemistry in Martinsried the Sonation column oven is used for the temperature regulation of the column in ESI-Nanospray applications. A constant column temperature makes measurements significantly more accurate, and a higher column temperature allows significantly higher flow rates to be achieved at a constant pressure. This leads to the fact that the sample and wash cycles can be accelerated considerably and thus the utilization of the instrument is improved.
Improving nanoESI
Sonation Nanospray Flex column ovens are developed with the goal to solve multiple problems in the ESI-Nanospray workflow:
- The influence of a changing room temperature
In most labs the room temperature is not constant. For example air conditions or opened doors cause a changing temperature that influences the results. - Limited length of the column due to the maximum pressure of the used HPLC.
The longer the used column, the higher the pressure must be to maintain the same flowrate. - The washout of the columns consumes a lot of time.
Even with the maximum pressure of the HPLC the washing cycles needs a lot of time. - RFID column identification
Label your column with a unique ID, physical dimensions and other useful data. You can also track the usage of your columns.
With the Sonation column oven the temperature of the column is now completely independent from the room temperature. You can also heat the column to high temperatures to accelerate the washout cycles or to get higher flowrates during the run. In addition to that the use of longer columns is now possible. You can adjust the temperature directly on the PC with the software that comes with the oven. You can also switch it between two temperatures automatically using an instrument method in Xcalibur.
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