Newomics MnESI-MS Platform

Robust Plug-and-Play platform, delivering High-Sensitivity and High-Throughput.

MnESI Platform = MnESI Source + M3 Emitter

The MnESI Source is Newomics new Microflow-nanospray Electrospray Ionization (MnESI) source that empowers Newomics award-winning M3 multinozzle emitters to multiply your mass spectrometry performance.

The M3 emitter has multiple nozzles working together to split a single microflow stream evenly into multiple nanoflows, thereby dramatically enhancing the ionization efficiency to achieve unprecedented sensitivity, robustness, and throughput. The applications have been successfully demonstrated for protein, peptide, lipid, and nucleic acid analysis by interfacing to mass spectrometers from multiple leading vendors.

Features and benefits

Empowers Newomics multinozzle emitters for significantly improved LC/MS performance.
Delivers nanoflow sensitivity and lower detection limit.
Allows smaller sample amount.
Enables higher sample throughput and faster analysis speed.
Achieves high robustness and excellent reproducibility for complex matrix analysis.
Visualizes spray via high quality imaging system.

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Specifications
Models and Compatiblity

Brochure & User Guides
Application Notes

MnESI Platform Specifications

Parameter	Specifications
Ionization Mode	Atmospheric pressure electrospray ionization (ESI), both positive and negative mode.
ESI Probe	Newomics M3 Emitter
Open or Closed System	Closed source
FlowRate	Nano (20 – 1000 nL/min) Micro (1-50 µL/min)
Spray Angle	Fixed angle of 25°
Spray Voltage	0 – 6 kV
Sheath Gas Flow Setting	0 – 30
Auxiliary Gas Flow Setting	0 – 20 (optional)
Translational Stage	Linear XY-axis manual stage, ±5 mm travel distance, 30 µm travel accuracy.
Camera	1.3M pixels, 20x-90x magnification rate, color CMOS sensor, up to 30 fps frame rate.
Light Source	Cool white (9000K) 5 mm round LED light, luminous intensity 46400 mcd.
Connection	Face seal, finger-tight 10-32 threaded fittings including Thermo nanoViper, IDEX MarvelX and MarvelXACT, Waters ZenFit, Phenomenex SecurityLink, VICI Cheminert C360IZR1, and nanoConnect
Unit Dimension	Width: 25 cm (9.8 in.) Height: 17,5 cm (6.9 in.) Depth: 15 cm (5.9 in.)
Unit Weight	3 kg

Click here to visit our online catalog, and request your quote for the MnESI-MS Platform.

Models and MS Compatibility

IS-T01

MnESI Source for Thermo Scientific New Generation Mass Spectrometers (e.g. Orbitrap Fusion Lumos, Eclipse, Exploris, and TSQ Altis Triple quadrupole mass spectrometers).
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For more information, download the User Guide for Thermo Scientific MS below.