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MnESI-MS Platform

Robust Plug-and-Play platform, delivering High-Sensitivity and High-Throughput.

MnESI Platform = MnESI Source + M3 Emitter

We are excited to introduce Newomics new Microflow-nanospray Electrospray Ionization (MnESI) source that empowers Newomics award-winning M3 multinozzle emitters to multiply your mass spectrometry performance.

Features and benefits

  • Empowers Newomics multinozzle emitters for significantly improved LC/MS performance.
  • Delivers nanoflow sensitivity and lower detection limit.
  • Allows smaller sample amount.
  • Enables higher sample throughput and faster analysis speed.
  • Achieves high robustness and excellent reproducibility for complex matrix analysis.
  • Visualizes spray via high quality imaging system.

MnESI Platform Specifications

Ionization ModeAtmospheric pressure electrospray ionization (ESI), both positive and negative mode.
ESI ProbeNewomics M3 Emitter
Open or Closed SystemClosed source
FlowRateNano (20 – 1000 nL/min)
Micro (1-50 µL/min)
Spray AngleFixed angle of 25°
Spray Voltage0 – 6 kV
Sheath Gas Flow Setting0 – 30
Auxiliary Gas Flow Setting0 – 20 (optional)
Translational StageLinear XY-axis manual stage, ±5 mm travel distance, 30 µm travel accuracy.
Camera1.3M pixels, 20x-90x magnification rate, color CMOS sensor, up to 30 fps frame rate.
Light SourceCool white (9000K) 5 mm round LED light, luminous intensity 46400 mcd.
ConnectionFace seal, finger-tight 10-32 threaded fittings including Thermo nanoViper, IDEX MarvelX and MarvelXACT,
Waters ZenFit, Phenomenex SecurityLink, VICI Cheminert C360IZR1, and nanoConnect
Unit DimensionWidth: 25 cm (9.8 in.)
Height: 17,5 cm (6.9 in.)
Depth: 15 cm (5.9 in.)
Unit Weight3 kg

Models and MS Compatibility


MnESI Source for Thermo Scientific New Generation Mass Spectrometers (e.g. Orbitrap Fusion Lumos, Eclipse, Exploris, and TSQ Altis Triple quadrupole mass spectrometers).


MnESI Source for Thermo Scientific Legacy Mass Spectrometers (e.g. Orbitrap Q Exactive mass spectrometers).


MnESI Source for Bruker Mass Spectrometers (e.g. maxis II QTOF, timsTOF Pro mass spectrometers).

For more information download the product brochure below:

MnESI Platform Brochure


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