Robust Plug-and-Play platform, delivering High-Sensitivity and High-Throughput.
MnESI Platform = MnESI Source + M3 Emitter
The MnESI Source is Newomics new Microflow-nanospray Electrospray Ionization (MnESI) source that empowers Newomics award-winning M3 multinozzle emitters to multiply your mass spectrometry performance.
Features and benefits
- Empowers Newomics multinozzle emitters for significantly improved LC/MS performance.
- Delivers nanoflow sensitivity and lower detection limit.
- Allows smaller sample amount.
- Enables higher sample throughput and faster analysis speed.
- Achieves high robustness and excellent reproducibility for complex matrix analysis.
- Visualizes spray via high quality imaging system.
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MnESI Platform Specifications
| Parameter | Specifications |
| Ionization Mode | Atmospheric pressure electrospray ionization (ESI), both positive and negative mode. |
| ESI Probe | Newomics M3 Emitter |
| Open or Closed System | Closed source |
| FlowRate | Nano (20 – 1000 nL/min) Micro (1-50 µL/min) |
| Spray Angle | Fixed angle of 25° |
| Spray Voltage | 0 – 6 kV |
| Sheath Gas Flow Setting | 0 – 30 |
| Auxiliary Gas Flow Setting | 0 – 20 (optional) |
| Translational Stage | Linear XY-axis manual stage, ±5 mm travel distance, 30 µm travel accuracy. |
| Camera | 1.3M pixels, 20x-90x magnification rate, color CMOS sensor, up to 30 fps frame rate. |
| Light Source | Cool white (9000K) 5 mm round LED light, luminous intensity 46400 mcd. |
| Connection | Face seal, finger-tight 10-32 threaded fittings including Thermo nanoViper, IDEX MarvelX and MarvelXACT, Waters ZenFit, Phenomenex SecurityLink, VICI Cheminert C360IZR1, and nanoConnect |
| Unit Dimension | Width: 25 cm (9.8 in.) Height: 17,5 cm (6.9 in.) Depth: 15 cm (5.9 in.) |
| Unit Weight | 3 kg |
Click here to visit our online catalog, and request your quote for the MnESI-MS Platform.
Models and MS Compatibility
IS-T01
MnESI Source for Thermo Scientific New Generation Mass Spectrometers (e.g. Orbitrap Fusion Lumos, Eclipse, Exploris, and TSQ Altis Triple quadrupole mass spectrometers).
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For more information, download the User Guide for Thermo Scientific MS below.
IS-T02
MnESI Source for Thermo Scientific Legacy Mass Spectrometers (e.g. Orbitrap Q Exactive mass spectrometers).
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For more information, download the User Guide for Thermo Scientific MS below.
IS-B01
MnESI Source for Bruker Mass Spectrometers (e.g. maxis II QTOF, timsTOF Pro mass spectrometers).
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For more information, download the User Guide for Bruker MS below.
IS-A01
MnESI Source for Agilent Mass Spectrometers
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Brochure & User Guides
MnESI Platform Brochure
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MnESI Ion Source for Thermo MS - User Guide
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MnESI Ion Source for Bruker MS - User Guide
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Application Notes
MnESI Platform for LC-MS Analysis of Native Protein Complexes
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MnESI Platform for Sensitive and Robust Analysis of Intact Antibodies
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MnESI Platform for Characterization of Intact NISTmAb under Native Conditions
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MnESI Platform for Small Molecules Analysis
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MnESI Platform for Sensitive Analysis of Oligonucleotides
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For more information on Newomics, click here.
