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Proteoform ProTrap XG

Sample Preparation delivering the highest purity with the greatest yield, in the simplest way possible.

The ProTrap XG is a dual-stage, disposable filtration and extraction cartridge that takes the guesswork out of precipitation and sample prep. Fueling precision medicine frontiers from therapeutics to vaccines to biomarker discovery, the ProTrap XG has been proven to remove more SDS than practically all other techniques available – delivering the highest purity with the greatest yield, in the simplest way possible.

Proteoforms solution brings this easy-to-use ProTrap XG tool together with reimagined protocols to generate highly purified, consistent, and reproducible samples, all at an accelerated pace.




ProTrap XG Features

  • Delivers 99.8% purity
  • Recovers >95% of proteins
  • Prepares samples in minutes
  • Easy to use
  • Eliminates time-consuming pipetting
  • Enables subsequent protein digestion, cleanup and fractionation all in one cartridge
  • Reduces risk of equipment contamination, damage, and expensive mass spectrometer downtime.
  • Supports streamlined workflows and training
  • Cost-effective per sample prepared
  • Brings consistency, scalability and versatility to sample prep




Clean samples = Less MS downtime

Achieving optimal protein characterization means working with the purest samples possible. Solvent precipitation is the best way to remove salts, lipids, and detergents from your sample, but it’s hard to perform consistently across multiple samples and multiple users. The ProTrap XG makes precipitation fast and easily reproducible.

End precipitation guess work & achieve better results

With the ProTrap XG, users no longer have to sacrifice sample loss for purity or vice versa. High recovery can now be achieved without having to rely on technique and expertise. The consistency of samples prepared in the ProTrap XG means better MS data outputs every single time.

Digestion, clean-up & fractionation – all in one device

Operating in bench-top centrifuge, the ProTrap XG offers users versatility, efficiency, and scalability in sample preparation.


Click here to request your quote for the ProTrap XG in our online catalog.



ProTrap XG vs. Other Methods

Many researchers find conventional methods of precipitation challenging, requiring tedious transfer and pipetting often leading to variable consistency and yield. Some methods show a loss of 50% or more of the sample, making analysis even more difficult. This tool eliminates tedious pipetting steps, offering consistency, method transferability, and versatility in the sample prep process.




Posters and Publications


For more information on Proteoform Scientific, click here.

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