CoAnn Technologies, LLC is dedicated to developing and manufacturing cutting-edge capillary separation columns and also related accessories and instruments. Especially those used with combination of mass spectrometry for measurement of complex mixtures such as objectives or Omics researches. We focus on making sensitive, high- resolution nanoLC columns with inner diameters of 15-100 μm and lengths of 20-120 cm. When coupled to advanced mass spectrometers, these columns provide the sensitivity needed for mapping of proteome heterogeneities at levels of a single or a few mammalian cells (~10 μm size), the resolution allowable for characterization of ~1,500 proteins and their >10,000 proteoforms in a proteome, as well as the power capable of measurement of >6,000 proteins through assignment of ~60,000 peptides. These nanoLC columns also help acquiring high quality mass spectral datasets for phosphopeptides, metabolites, and other small biological and chemical molecules.
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